Sarah secures NHMRC funding to continue her Catalase / Peroxisomal research

Congratulations to Dr Sarah Withey on receiving $781,640 in the recent round of NHMRC grants. The funding will allow her to continue her research into a potential therapy for A-T using mini brain and liver organoids.

Using brain and liver organoids (tiny, three-dimensional organ avatars, made from the cells of patients living with A-T) researchers have discovered deficiency of a key protein involved in protecting DNA from damage.

This grant will support Sarah and her team at the AIBN to test if a modified therapeutic can repair the function to this protein, which could lead to improvement in some of the life limiting symptoms of A-T.

Dose Response and Mechanistic Profiling of Two Candidate Neuroactive Drugs in A-T Cerebellar Organoids

We are delighted to be supporting this “follow on” project at the QIMR Berghofer Medical Research Institute in partnership with Action for A-T (UK).

The project led by Dr Sam Nayler will test two potential drug targets on mini brain organoids to gauge their efficacy.

This $120,000 12-month project will commence in February 2026 and will be managed by Action for A-T.

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